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Clodronate Liposome And The Importance Of Its Discovery

By Roxanne Cruz


Before, thousands of residents die because certain medicine or vaccination was not yet available in the market. However, due to the discoveries of these geniuses, curing the once deadly diseases are now possible. Since medical science plays a very fascinating role in medicine science, clodronate liposome was discovered, accidentally. Because of the great role it plays in curing and treating diseases, it will surely be of great importance to medical science.

Clodronate also known as clodronate disodium and clodronic acid is a first generation non nitrogenous bisphosphonate. It is a drug scientifically approved, tested, and used to prevent and treat the cases of osteoporosis especially to the women who have reached the post menopausal period. It is also used in the experimental medicine to deplete macrophages.

These are white blood cells within tissues. Macrophages are produced by the division of the white blood cells formed in the bone marrow and spleen. These kind of white blood cell is known to be as monocytes which ingest foreign particles after it was formed. Basically, macrophage is the core of the system which fight against infectious viruses and diseases.

Liposomes are the microscopic bubbles which are consist of fatty liquids. These are used in cell biology to study the cell and find cures to any diseases found in the cell. They are drugs that are used to help treat and cure cancer. But it does not only limit to cancer, scientists also approved that these drugs can be used in curing other diseases. It is made of liquid and phospholipids.

Science discovered clodronate liposome acts for the suppression of the macrophage. Indeed immune system defends the invasion of infectious viruses and bacteria. Through immune response, it will attack the invaders that will cause diseases to the organ or body. However, the immune system can be the source of disease in the body.

In normal circumstances, a healthy immune system will help in dealing with sickness such as colds, fever and coughs. They functions as the defender from illnesses and diseases. On the other way around, a damaged one will result to your own cells attacking the healthy cells. When this happens, various severe medical disorders will affect the body.

As mentioned earlier, immune response protects the body from viral invasion. However, several damages will lead to grave autoimmune medical conditions caused by transplant rejection. This transplant rejection is one of the effects of the response. As a new organ in places on the transplant patient, cells will incite the system to attack the organ cells that will lead to rejection.

Medical people discovered a certain drug that will treat and cure cases like those. This is made of bisphosphonate the will lessen macrophage. It will be transplanted to the organ cell and as soon as it detected that it is foreign, it will automatically cover the whole transplant up and try to eat them through the so called phagocytosis.

Clodronate liposome is said to treat cancer through the increase absorption of plasma. It also improves the effects of anti tumor drugs to treat cancer. Even if this discovery is really fascinating, consult the medical doctor first before deciding to take this drug. This is for your safety, after all.




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